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A multistate tuberculosis pharmacometric model: a framework for studying anti-tubercular drug effects in vitro

OBJECTIVES: Mycobacterium tuberculosis can exist in different states in vitro, which can be denoted as fast multiplying, slow multiplying and non-multiplying. Characterizing the natural growth of M. tuberculosis could provide a framework for accurate characterization of drug effects on the different...

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Detalles Bibliográficos
Autores principales: Clewe, Oskar, Aulin, Linda, Hu, Yanmin, Coates, Anthony R. M., Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790616/
https://www.ncbi.nlm.nih.gov/pubmed/26702921
http://dx.doi.org/10.1093/jac/dkv416