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Gradients in pore size enhance the osteogenic differentiation of human mesenchymal stromal cells in three-dimensional scaffolds

Small fractures in bone tissue can heal by themselves, but in case of larger defects current therapies are not completely successful due to several drawbacks. A possible strategy relies on the combination of additive manufactured polymeric scaffolds and human mesenchymal stromal cells (hMSCs). The a...

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Detalles Bibliográficos
Autores principales: Di Luca, Andrea, Ostrowska, Barbara, Lorenzo-Moldero, Ivan, Lepedda, Antonio, Swieszkowski, Wojcech, Van Blitterswijk, Clemens, Moroni, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790631/
https://www.ncbi.nlm.nih.gov/pubmed/26961859
http://dx.doi.org/10.1038/srep22898