A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus

3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase, a mevalonate synthetase, is required for the growth of Staphylococcus aureus. However, the essential role of the enzyme in cell growth has remained unclear. Here we show that three mutants possessed single-base substitutions in the mvaA gene, whic...

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Detalles Bibliográficos
Autores principales: Matsumoto, Yasuhiko, Yasukawa, Jyunichiro, Ishii, Masaki, Hayashi, Yohei, Miyazaki, Shinya, Sekimizu, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790635/
https://www.ncbi.nlm.nih.gov/pubmed/26961421
http://dx.doi.org/10.1038/srep22894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790635/
https://www.ncbi.nlm.nih.gov/pubmed/26961421
http://dx.doi.org/10.1038/srep22894

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