Uric acid enhances PKC-dependent eNOS phosphorylation and mediates cellular ER stress: A mechanism for uric acid-induced endothelial dysfunction

The mechanism by which hyperuricemia induced-endothelial dysfunction contributes to cardiovascular diseases (CVDs) is not yet fully understood. In the present study, we used uric acid (UA) to trigger endothelial dysfunction in cultured endothelial cells, and investigated the effects of induced react...

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Detalles Bibliográficos
Autores principales: LI, PENG, ZHANG, LINA, ZHANG, MEI, ZHOU, CHANGYONG, LIN, NAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790645/
https://www.ncbi.nlm.nih.gov/pubmed/26935704
http://dx.doi.org/10.3892/ijmm.2016.2491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790645/
https://www.ncbi.nlm.nih.gov/pubmed/26935704
http://dx.doi.org/10.3892/ijmm.2016.2491

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