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Role of Alix in miRNA packaging during extracellular vesicle biogenesis

Evidence indicates that Alix, an accessory protein of the endosomal sorting complex required for transport (ESCRT), is involved in the biogenesis of extracellular vesicles (EVs). EVs contain selected patterns of microRNAs (miRNAs or miRs); however, little is known about the mechanisms of miRNA enric...

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Detalles Bibliográficos
Autores principales: IAVELLO, ALESSANDRA, FRECH, VALESKA S.L., GAI, CHIARA, DEREGIBUS, MARIA CHIARA, QUESENBERRY, PETER J., CAMUSSI, GIOVANNI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790646/
https://www.ncbi.nlm.nih.gov/pubmed/26935291
http://dx.doi.org/10.3892/ijmm.2016.2488