Exendin-4 protects bone marrow-derived mesenchymal stem cells against oxygen/glucose and serum deprivation-induced apoptosis through the activation of the cAMP/PKA signaling pathway and the attenuation of ER stress

Exendin-4 (ex-4) is a long-acting glucagon-like peptide-1 receptor (GLP-1R) agonist which exerts beneficial effects on glycemic control and promotes cell viability. In the present study, we investigated the anti-apoptotic effects of ex-4, as well as the potential mechanisms responsible for these eff...

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Detalles Bibliográficos
Autores principales: HE, JIEQIONG, WANG, CHAO, SUN, YUNPENG, LU, BO, CUI, JINJIN, DONG, NANA, ZHANG, MAOMAO, LIU, YOUBING, YU, BO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790651/
https://www.ncbi.nlm.nih.gov/pubmed/26935620
http://dx.doi.org/10.3892/ijmm.2016.2509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790651/
https://www.ncbi.nlm.nih.gov/pubmed/26935620
http://dx.doi.org/10.3892/ijmm.2016.2509

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