Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes

It has long been thought that iminosugar antiviral activity is a function of inhibition of endoplasmic reticulum-resident α-glucosidases, and on this basis, many iminosugars have been investigated as therapeutic agents for treatment of infection by a diverse spectrum of viruses, including dengue vir...

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Detalles Bibliográficos
Autores principales: Sayce, Andrew C., Alonzi, Dominic S., Killingbeck, Sarah S., Tyrrell, Beatrice E., Hill, Michelle L., Caputo, Alessandro T., Iwaki, Ren, Kinami, Kyoko, Ide, Daisuke, Kiappes, J. L., Beatty, P. Robert, Kato, Atsushi, Harris, Eva, Dwek, Raymond A., Miller, Joanna L., Zitzmann, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790851/
https://www.ncbi.nlm.nih.gov/pubmed/26974655
http://dx.doi.org/10.1371/journal.pntd.0004524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790851/
https://www.ncbi.nlm.nih.gov/pubmed/26974655
http://dx.doi.org/10.1371/journal.pntd.0004524

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