Experimental Persistent Infection of BALB/c Mice with Small-Colony Variants of Burkholderia pseudomallei Leads to Concurrent Upregulation of PD-1 on T Cells and Skewed Th1 and Th17 Responses

BACKGROUND: Burkholderia pseudomallei (B. pseudomallei), the causative agent of melioidosis, is a deadly pathogen endemic across parts of tropical South East Asia and Northern Australia. B. pseudomallei can remain latent within the intracellular compartment of the host cell over prolonged periods of...

Descripción completa

Detalles Bibliográficos
Autores principales: See, Jia-Xiang, Samudi, Chandramathi, Saeidi, Alireza, Menon, Nivedita, Choh, Leang-Chung, Vadivelu, Jamuna, Shankar, Esaki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790896/
https://www.ncbi.nlm.nih.gov/pubmed/26974441
http://dx.doi.org/10.1371/journal.pntd.0004503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790896/
https://www.ncbi.nlm.nih.gov/pubmed/26974441
http://dx.doi.org/10.1371/journal.pntd.0004503

Ejemplares similares