Experimental Persistent Infection of BALB/c Mice with Small-Colony Variants of Burkholderia pseudomallei Leads to Concurrent Upregulation of PD-1 on T Cells and Skewed Th1 and Th17 Responses

BACKGROUND: Burkholderia pseudomallei (B. pseudomallei), the causative agent of melioidosis, is a deadly pathogen endemic across parts of tropical South East Asia and Northern Australia. B. pseudomallei can remain latent within the intracellular compartment of the host cell over prolonged periods of...

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Detalles Bibliográficos
Autores principales: See, Jia-Xiang, Samudi, Chandramathi, Saeidi, Alireza, Menon, Nivedita, Choh, Leang-Chung, Vadivelu, Jamuna, Shankar, Esaki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790896/
https://www.ncbi.nlm.nih.gov/pubmed/26974441
http://dx.doi.org/10.1371/journal.pntd.0004503

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