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Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway

Though hypoxia has been implicated as a cause of inflammation, the underlying mechanism is not well understood. Folic acid has been shown to provide protection against oxidative stress and inflammation in patients with cardiovascular disease and various models approximating insult to tissue via infl...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoyan, He, Zhiying, Jiang, Xinwei, Hou, Mengjun, Tang, Zhihong, Zhen, Xiaozhou, Liang, Yuming, Ma, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790958/
https://www.ncbi.nlm.nih.gov/pubmed/26974319
http://dx.doi.org/10.1371/journal.pone.0151553