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Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway
Though hypoxia has been implicated as a cause of inflammation, the underlying mechanism is not well understood. Folic acid has been shown to provide protection against oxidative stress and inflammation in patients with cardiovascular disease and various models approximating insult to tissue via infl...
Autores principales: | Huang, Xiaoyan, He, Zhiying, Jiang, Xinwei, Hou, Mengjun, Tang, Zhihong, Zhen, Xiaozhou, Liang, Yuming, Ma, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790958/ https://www.ncbi.nlm.nih.gov/pubmed/26974319 http://dx.doi.org/10.1371/journal.pone.0151553 |
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