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Pathogen Inactivating Properties and Increased Sensitivity in Molecular Diagnostics by PAXgene, a Novel Non-Crosslinking Tissue Fixative

BACKGROUND: Requirements on tissue fixatives are getting more demanding as molecular analysis becomes increasingly relevant for routine diagnostics. Buffered formaldehyde in pathology laboratories for tissue fixation is known to cause chemical modifications of biomolecules which affect molecular tes...

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Detalles Bibliográficos
Autores principales: Loibner, Martina, Buzina, Walter, Viertler, Christian, Groelz, Daniel, Hausleitner, Anja, Siaulyte, Gintare, Kufferath, Iris, Kölli, Bettina, Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790970/
https://www.ncbi.nlm.nih.gov/pubmed/26974150
http://dx.doi.org/10.1371/journal.pone.0151383