Drosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation

Drosophila Nedd4 (dNedd4) is a HECT ubiquitin ligase with two main splice isoforms: dNedd4-short (dNedd4S) and -long (dNedd4Lo). DNedd4Lo has a unique N-terminus containing a Pro-rich region. We previously showed that whereas dNedd4S promotes neuromuscular synaptogenesis, dNedd4Lo inhibits it and im...

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Detalles Bibliográficos
Autores principales: Safi, Frozan, Shteiman-Kotler, Alina, Zhong, Yunan, Iliadi, Konstantin G., Boulianne, Gabrielle L., Rotin, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791135/
https://www.ncbi.nlm.nih.gov/pubmed/26823013
http://dx.doi.org/10.1091/mbc.E15-06-0420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791135/
https://www.ncbi.nlm.nih.gov/pubmed/26823013
http://dx.doi.org/10.1091/mbc.E15-06-0420

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