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Stability and flexibility of marginally hydrophobic–segment stalling at the endoplasmic reticulum translocon

Many membrane proteins are integrated into the endoplasmic reticulum membrane through the protein-conducting channel, the translocon. Transmembrane segments with insufficient hydrophobicity for membrane integration are frequently found in multispanning membrane proteins, and such marginally hydropho...

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Detalles Bibliográficos
Autores principales: Kida, Yuichiro, Ishihara, Yudai, Fujita, Hidenobu, Onishi, Yukiko, Sakaguchi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791137/
https://www.ncbi.nlm.nih.gov/pubmed/26823014
http://dx.doi.org/10.1091/mbc.E15-09-0672