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Interplay between Solo and keratin filaments is crucial for mechanical force–induced stress fiber reinforcement

Mechanical force–induced cytoskeletal reorganization is essential for cell and tissue remodeling and homeostasis; however, the underlying cellular mechanisms remain elusive. Solo (ARHGEF40) is a RhoA-targeting guanine nucleotide exchange factor (GEF) involved in cyclical stretch–induced human endoth...

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Detalles Bibliográficos
Autores principales: Fujiwara, Sachiko, Ohashi, Kazumasa, Mashiko, Toshiya, Kondo, Hiroshi, Mizuno, Kensaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791139/
https://www.ncbi.nlm.nih.gov/pubmed/26823019
http://dx.doi.org/10.1091/mbc.E15-06-0417