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Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1

C2 domains are widespread motifs that often serve as Ca(2+)-binding modules; some proteins have more than one copy. An open issue is whether these domains, when duplicated within the same parent protein, interact with one another to regulate function. In the present study, we address the functional...

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Detalles Bibliográficos
Autores principales: Evans, Chantell S., He, Zixuan, Bai, Hua, Lou, Xiaochu, Jeggle, Pia, Sutton, R. Bryan, Edwardson, J. Michael, Chapman, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791141/
https://www.ncbi.nlm.nih.gov/pubmed/26792839
http://dx.doi.org/10.1091/mbc.E15-07-0503