LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although lncRNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely un...

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Detalles Bibliográficos
Autores principales: Xue, Xingyang, Yang, Yeqing Angela, Zhang, Ali, Fong, Ka-wing, Kim, Jung, Song, Bing, Li, Shangze, Zhao, Jonathan C., Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791209/
https://www.ncbi.nlm.nih.gov/pubmed/26364613
http://dx.doi.org/10.1038/onc.2015.340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791209/
https://www.ncbi.nlm.nih.gov/pubmed/26364613
http://dx.doi.org/10.1038/onc.2015.340

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