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IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival

The chromatin-binding DEK protein was recently reported to promote the growth of HPV(+) and HPV(−) head and neck squamous cell carcinomas (HNSCCs). Relevant cellular and molecular mechanism(s) controlled by DEK in HNSCC remain poorly understood. While DEK is known to regulate specific transcriptiona...

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Detalles Bibliográficos
Autores principales: Adams, Allie K., Bolanos, Lyndsey C., Dexheimer, Phillip J., Karns, Rebekah A., Aronow, Bruce J., Komurov, Kakajan, Jegga, Anil G., Casper, Keith A., Patil, Yash J., Wilson, Keith M., Starczynowski, Daniel T., Wells, Susanne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791239/
https://www.ncbi.nlm.nih.gov/pubmed/26527316