Collective cancer cell invasion induced by coordinated contractile stresses

The physical underpinnings of fibrosarcoma cell dissemination from a tumor in a surrounding collagen-rich matrix are poorly understood. Here we show that a tumor spheroid embedded in a 3D collagen matrix exerts large contractile forces on the matrix before invasion. Cell invasion is accompanied by c...

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Detalles Bibliográficos
Autores principales: Valencia, Angela M. Jimenez, Wu, Pei-Hsun, Yogurtcu, Osman N., Rao, Pranay, DiGiacomo, Josh, Godet, Inês, He, Lijuan, Lee, Meng-Horng, Gilkes, Daniele, Sun, Sean X., Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791242/
https://www.ncbi.nlm.nih.gov/pubmed/26528856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791242/
https://www.ncbi.nlm.nih.gov/pubmed/26528856

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