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Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells

Stress granules (SGs) are cytoplasmic RNA multimeric bodies that form under stress conditions known to inhibit translation initiation. In most reported stress cases, the formation of SGs was associated with the cell recovery from stress and survival. In cells derived from cancer, SGs formation was s...

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Detalles Bibliográficos
Autores principales: Adjibade, Pauline, St-Sauveur, Valérie Grenier, Huberdeau, Miguel Quevillon, Fournier, Marie-Josée, Savard, Andreanne, Coudert, Laetitia, Khandjian, Edouard W., Mazroui, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791277/
https://www.ncbi.nlm.nih.gov/pubmed/26556863