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The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells

Exosomes, extracellular nanovesicles secreted by various cell types, modulate the bone marrow (BM) microenvironment by regulating angiogenesis, cytokine release, immune response, inflammation, and metastasis. Interactions between bone marrow stromal cells (BMSCs) and multiple myeloma (MM) cells play...

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Detalles Bibliográficos
Autores principales: Wang, Jinheng, De Veirman, Kim, De Beule, Nathan, Maes, Ken, De Bruyne, Elke, Van Valckenborgh, Els, Vanderkerken, Karin, Menu, Eline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791281/
https://www.ncbi.nlm.nih.gov/pubmed/26556857