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Lidocaine Inhibits HCN Currents in Rat Spinal Substantia Gelatinosa Neurons

Lidocaine, which blocks voltage-gated sodium channels, is widely used in surgical anesthesia and pain management. Recently, it has been proposed that the hyperpolarization-activated cyclic nucleotide (HCN) channel is one of the other novel targets of lidocaine. Substantia gelatinosa in the spinal do...

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Detalles Bibliográficos
Autores principales: Hu, Tao, Liu, Nana, Lv, Minhua, Ma, Longxian, Peng, Huizhen, Peng, Sicong, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
9
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791316/
https://www.ncbi.nlm.nih.gov/pubmed/26756913
http://dx.doi.org/10.1213/ANE.0000000000001140