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Lidocaine Inhibits HCN Currents in Rat Spinal Substantia Gelatinosa Neurons
Lidocaine, which blocks voltage-gated sodium channels, is widely used in surgical anesthesia and pain management. Recently, it has been proposed that the hyperpolarization-activated cyclic nucleotide (HCN) channel is one of the other novel targets of lidocaine. Substantia gelatinosa in the spinal do...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791316/ https://www.ncbi.nlm.nih.gov/pubmed/26756913 http://dx.doi.org/10.1213/ANE.0000000000001140 |