Cargando…

Single-molecule fluorescence measurements reveal the reaction mechanisms of the core-RISC, composed of human Argonaute 2 and a guide RNA

In eukaryotes, small RNAs play important roles in both gene regulation and resistance to viral infection. Argonaute proteins have been identified as a key component of the effector complexes of various RNA-silencing pathways, but the mechanistic roles of Argonaute proteins in these pathways are not...

Descripción completa

Detalles Bibliográficos
Autores principales: Jo, Myung Hyun, Song, Ji-Joon, Hohng, Sungchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791318/
https://www.ncbi.nlm.nih.gov/pubmed/26592935
http://dx.doi.org/10.5483/BMBRep.2015.48.12.235