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Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells

We report that phytosphingosine, a sphingolipid found in many organisms and implicated in cellular signaling, promotes megakaryocytic differentiation of myeloid leukemia cells. Specifically, phytosphingosine induced several hallmark changes associated with megakaryopoiesis from K562 and HEL cells in...

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Detalles Bibliográficos
Autores principales: Han, Sang Hee, Kim, Jusong, Her, Yerim, Seong, Ikjoo, Park, Sera, Bhattarai, Deepak, Jin, Guanghai, Lee, Kyeong, Chung, Gukhoon, Hwang, Sungkee, Bae, Yun Soo, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791325/
https://www.ncbi.nlm.nih.gov/pubmed/26077028
http://dx.doi.org/10.5483/BMBRep.2015.48.12.100