Cargando…

An inhibitory alternative splice isoform of Toll-like receptor 3 is induced by type I interferons in human astrocyte cell lines

Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA. It stimulates pro-inflammatory cytokine and interferon production. Here we reported the expression of a novel isoform of TLR3 in human astrocyte cell lines whose message is generated by alternative splicing. The isoform represents the...

Descripción completa

Detalles Bibliográficos
Autores principales: Seo, Jin-Won, Yang, Eun-Jeong, Kim, Se Hoon, Choi, In-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791326/
https://www.ncbi.nlm.nih.gov/pubmed/26077030
http://dx.doi.org/10.5483/BMBRep.2015.48.12.106