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An inhibitory alternative splice isoform of Toll-like receptor 3 is induced by type I interferons in human astrocyte cell lines
Toll-like receptor 3 (TLR3) recognizes viral double-stranded RNA. It stimulates pro-inflammatory cytokine and interferon production. Here we reported the expression of a novel isoform of TLR3 in human astrocyte cell lines whose message is generated by alternative splicing. The isoform represents the...
Autores principales: | Seo, Jin-Won, Yang, Eun-Jeong, Kim, Se Hoon, Choi, In-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791326/ https://www.ncbi.nlm.nih.gov/pubmed/26077030 http://dx.doi.org/10.5483/BMBRep.2015.48.12.106 |
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