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Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced Activity
Cells have evolved a sophisticated proteostasis network to ensure that proteins acquire and retain their native structure and function. Critical components of this network include molecular chaperones and protein disaggregases, which function to prevent and reverse deleterious protein misfolding. Ne...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791398/ https://www.ncbi.nlm.nih.gov/pubmed/27014702 http://dx.doi.org/10.3389/fmolb.2016.00008 |