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Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced Activity

Cells have evolved a sophisticated proteostasis network to ensure that proteins acquire and retain their native structure and function. Critical components of this network include molecular chaperones and protein disaggregases, which function to prevent and reverse deleterious protein misfolding. Ne...

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Detalles Bibliográficos
Autores principales: Mack, Korrie L., Shorter, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791398/
https://www.ncbi.nlm.nih.gov/pubmed/27014702
http://dx.doi.org/10.3389/fmolb.2016.00008