RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes

Development of alternatively activated (M2) macrophage phenotypes is a complex process that is coordinately regulated by a plethora of pathways and factors. Here, we report that RBP-J, a DNA-binding protein that integrates signals from multiple pathways including the Notch pathway, is critically inv...

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Detalles Bibliográficos
Autores principales: Foldi, Julia, Shang, Yingli, Zhao, Baohong, Ivashkiv, Lionel B., Hu, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791428/
https://www.ncbi.nlm.nih.gov/pubmed/26874522
http://dx.doi.org/10.1007/s13238-016-0248-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791428/
https://www.ncbi.nlm.nih.gov/pubmed/26874522
http://dx.doi.org/10.1007/s13238-016-0248-7

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