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RBP-J is required for M2 macrophage polarization in response to chitin and mediates expression of a subset of M2 genes
Development of alternatively activated (M2) macrophage phenotypes is a complex process that is coordinately regulated by a plethora of pathways and factors. Here, we report that RBP-J, a DNA-binding protein that integrates signals from multiple pathways including the Notch pathway, is critically inv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791428/ https://www.ncbi.nlm.nih.gov/pubmed/26874522 http://dx.doi.org/10.1007/s13238-016-0248-7 |