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Deficiency of Lipocalin-2 Promotes Proliferation and Differentiation of Osteoclast Precursors via Regulation of c-Fms Expression and Nuclear Factor-kappa B Activation

BACKGROUND: Lipocalin-2 (LCN2), a small glycoprotein, has a pivotal role in diverse biological processes such as cellular proliferation and differentiation. We previously reported that LCN2 is implicated in osteoclast formation induced by receptor activator of nuclear factor-kappa B ligand (RANKL) a...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Ju, Ohk, Boram, Kang, Woo Youl, Seong, Sook Jin, Suk, Kyoungho, Lim, Mi-Sun, Kim, Shin-Yoon, Yoon, Young-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791440/
https://www.ncbi.nlm.nih.gov/pubmed/26981515
http://dx.doi.org/10.11005/jbm.2016.23.1.8