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Impact of New Genomic Technologies on Understanding Adverse Drug Reactions
It is well established that variations in genes can alter the pharmacokinetic and pharmacodynamic profile of a drug and immunological responses to it. Early advances in pharmacogenetics were made with traditional genetic techniques such as functional cloning of genes using knowledge gained from puri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791456/ https://www.ncbi.nlm.nih.gov/pubmed/26369774 http://dx.doi.org/10.1007/s40262-015-0324-9 |