Input estimation for drug discovery using optimal control and Markov chain Monte Carlo approaches

Input estimation is employed in cases where it is desirable to recover the form of an input function which cannot be directly observed and for which there is no model for the generating process. In pharmacokinetic and pharmacodynamic modelling, input estimation in linear systems (deconvolution) is w...

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Detalles Bibliográficos
Autores principales: Trägårdh, Magnus, Chappell, Michael J., Ahnmark, Andrea, Lindén, Daniel, Evans, Neil D., Gennemark, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791487/
https://www.ncbi.nlm.nih.gov/pubmed/26932466
http://dx.doi.org/10.1007/s10928-016-9467-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791487/
https://www.ncbi.nlm.nih.gov/pubmed/26932466
http://dx.doi.org/10.1007/s10928-016-9467-z

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