Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis

Hereditary Parkinson's disease can be triggered by an autosomal dominant overdose of alpha-Synuclein (SNCA) or the autosomal recessive deficiency of PINK1. We recently showed that the combination of PINK1-knockout with overexpression of A53T-SNCA in double mutant (DM) mice potentiates phenotype...

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Detalles Bibliográficos
Autores principales: Auburger, Georg, Gispert, Suzana, Brehm, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791501/
https://www.ncbi.nlm.nih.gov/pubmed/27034888
http://dx.doi.org/10.1155/2016/4686185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791501/
https://www.ncbi.nlm.nih.gov/pubmed/27034888
http://dx.doi.org/10.1155/2016/4686185

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