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Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers

Increased reactive oxygen species (ROS) generation and the ensuing oxidative stress contribute to Alzheimer's disease pathology. We reported previously that amyloid-β peptide oligomers (AβOs) produce aberrant Ca(2+) signals at sublethal concentrations and decrease the expression of type-2 ryano...

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Detalles Bibliográficos
Autores principales: Lobos, Pedro, Bruna, Barbara, Cordova, Alex, Barattini, Pablo, Galáz, Jose Luis, Adasme, Tatiana, Hidalgo, Cecilia, Muñoz, Pablo, Paula-Lima, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791503/
https://www.ncbi.nlm.nih.gov/pubmed/27034843
http://dx.doi.org/10.1155/2016/3456783