Cargando…

MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B

The histone variant, macroH2A1, has an important role in embryonic stem cell differentiation and tumor progression in various types of tumors. However, the regulatory roles of macroH2A1 on bladder cancer progression have not been fully elucidated. Here, we show that macroH2A1 knockdown promotes stem...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, S-J, Shim, J W, Park, H S, Eum, D-Y, Park, M-T, Mi Yi, J, Choi, S H, Kim, S D, Son, T G, Lu, W, Kim, N D, Yang, K, Heo, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791524/
https://www.ncbi.nlm.nih.gov/pubmed/26028027
http://dx.doi.org/10.1038/onc.2015.187