Impact of 4-epi-oxytetracycline on the gut microbiota and blood metabolomics of Wistar rats

The impact of 4-epi-oxytetracycline (4-EOTC), one of the main oxytetracycline (OTC) metabolites, on the gut microbiota and physiological metabolism of Wistar rats was analyzed to explore the dynamic alterations apparent after repeated oral exposure (0.5, 5.0 or 50.0 mg/kg bw) for 15 days as shown by...

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Detalles Bibliográficos
Autores principales: Han, Hongxing, Xiao, Hailong, Zhang, Kai, Lu, Zhenmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791543/
https://www.ncbi.nlm.nih.gov/pubmed/26976662
http://dx.doi.org/10.1038/srep23141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791543/
https://www.ncbi.nlm.nih.gov/pubmed/26976662
http://dx.doi.org/10.1038/srep23141

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