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Dissection and integration of the autophagy signaling network initiated by bluetongue virus infection: crucial candidates ERK1/2, Akt and AMPK

Bluetongue virus (BTV), a complex double-stranded segmented RNA virus, has been found to initiate cellular autophagy for its own benefit. Here, with a view to understanding the underlying mechanisms, we first systematically dissected the exact signaling network in BTV-induced autophagy. We found tha...

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Detalles Bibliográficos
Autores principales: Lv, Shuang, Xu, Qing-Yuan, Sun, En-Cheng, Zhang, Ji-Kai, Wu, Dong-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791558/
https://www.ncbi.nlm.nih.gov/pubmed/26976147
http://dx.doi.org/10.1038/srep23130