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Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?
[Image: see text] High-throughput biology has contributed a wealth of data on chemicals, including natural products (NPs). Recently, attention was drawn to certain, predominantly synthetic, compounds that are responsible for disproportionate percentages of hits but are false actives. Spurious bioass...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791574/ https://www.ncbi.nlm.nih.gov/pubmed/26505758 http://dx.doi.org/10.1021/acs.jmedchem.5b01009 |