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Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells

Leishmania and Trypanosoma are unicellular parasites that possess markedly original biological features as compared to other eukaryotes. The Leishmania genome displays a constitutive ‘mosaic aneuploidy’, whereas in Trypanosoma brucei, the megabase-sized chromosomes are diploid. We accurately analyse...

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Detalles Bibliográficos
Autores principales: Stanojcic, Slavica, Sollelis, Lauriane, Kuk, Nada, Crobu, Lucien, Balard, Yves, Schwob, Etienne, Bastien, Patrick, Pagès, Michel, Sterkers, Yvon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791591/
https://www.ncbi.nlm.nih.gov/pubmed/26976742
http://dx.doi.org/10.1038/srep23142