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Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets

Allogeneic stem cell transplantation (alloSCT) can be a curative treatment for hematological malignancies. Unfortunately, the desired anti-tumor or graft-versus-leukemia (GvL) effect is often accompanied with undesired side effects against healthy tissues known as graft-versus-host disease (GvHD). A...

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Detalles Bibliográficos
Autores principales: Griffioen, Marieke, van Bergen, Cornelis A. M., Falkenburg, J. H. Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791598/
https://www.ncbi.nlm.nih.gov/pubmed/27014279
http://dx.doi.org/10.3389/fimmu.2016.00100