Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype

Sprouty (Spry) proteins have been implicated in cancer progression, but their role in triple-negative breast cancer (TNBC), a subtype of lethal and aggressive breast cancer, is unknown. Here, we reported that Spry1 is significantly expressed in TNBC specimen and MDA-MB-231 cells. To understand Spry1...

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Detalles Bibliográficos
Autores principales: He, Qing, Jing, Hongyu, Liaw, Lucy, Gower, Lindsey, Vary, Calvin, Hua, Shucheng, Yang, Xuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791662/
https://www.ncbi.nlm.nih.gov/pubmed/26976794
http://dx.doi.org/10.1038/srep23216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791662/
https://www.ncbi.nlm.nih.gov/pubmed/26976794
http://dx.doi.org/10.1038/srep23216

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