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Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression

Repeated stressful events are associated with the onset of major depressive disorder (MDD). We previously showed oligodendrocyte (OL)-specific activation of the serum/glucocorticoid-regulated kinase (SGK)1 cascade, increased expression of axon-myelin adhesion molecules, and elaboration of the oligod...

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Detalles Bibliográficos
Autores principales: Miyata, Shingo, Taniguchi, Manabu, Koyama, Yoshihisa, Shimizu, Shoko, Tanaka, Takashi, Yasuno, Fumihiko, Yamamoto, Akihide, Iida, Hidehiro, Kudo, Takashi, Katayama, Taiichi, Tohyama, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791682/
https://www.ncbi.nlm.nih.gov/pubmed/26976207
http://dx.doi.org/10.1038/srep23084