Cargando…
Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression
Repeated stressful events are associated with the onset of major depressive disorder (MDD). We previously showed oligodendrocyte (OL)-specific activation of the serum/glucocorticoid-regulated kinase (SGK)1 cascade, increased expression of axon-myelin adhesion molecules, and elaboration of the oligod...
Autores principales: | Miyata, Shingo, Taniguchi, Manabu, Koyama, Yoshihisa, Shimizu, Shoko, Tanaka, Takashi, Yasuno, Fumihiko, Yamamoto, Akihide, Iida, Hidehiro, Kudo, Takashi, Katayama, Taiichi, Tohyama, Masaya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791682/ https://www.ncbi.nlm.nih.gov/pubmed/26976207 http://dx.doi.org/10.1038/srep23084 |
Ejemplares similares
-
Plasma Corticosterone Activates SGK1 and Induces Morphological Changes in Oligodendrocytes in Corpus Callosum
por: Miyata, Shingo, et al.
Publicado: (2011) -
The Endoplasmic Reticulum-Resident Chaperone Heat Shock Protein 47 Protects the Golgi Apparatus from the Effects of O-Glycosylation Inhibition
por: Miyata, Shingo, et al.
Publicado: (2013) -
NDE1 positively regulates oligodendrocyte morphological differentiation
por: Shimizu, Shoko, et al.
Publicado: (2018) -
DISC1 (Disrupted-in-Schizophrenia-1) Regulates Differentiation of Oligodendrocytes
por: Hattori, Tsuyoshi, et al.
Publicado: (2014) -
Disturbance of Oligodendrocyte Function Plays a Key Role in the Pathogenesis of Schizophrenia and Major Depressive Disorder
por: Miyata, Shingo, et al.
Publicado: (2015)