Yeast-based assays for screening 11β-HSD1 inhibitors

BACKGROUND: Intracellular metabolism of glucocorticoid hormones plays an important role in the pathogenesis of metabolic syndrome and regulates, among many physiological processes, collagen metabolism in skin. At the peripheral level the concentration of active glucocorticoids is mainly regulated by...

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Detalles Bibliográficos
Autores principales: Vanella, Rosario, Callari, Roberta, Weston, Anna, Heider, Harald, Schwab, Markus S., Kübler, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791775/
https://www.ncbi.nlm.nih.gov/pubmed/26980090
http://dx.doi.org/10.1186/s12934-016-0450-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791775/
https://www.ncbi.nlm.nih.gov/pubmed/26980090
http://dx.doi.org/10.1186/s12934-016-0450-6

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