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Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study
BACKGROUND: We previously reported that talimogene laherparepvec, an oncolytic herpes virus encoding granulocyte-macrophage colony-stimulating factor (GM-CSF), resulted in an objective response rate of 26 % in patients with advanced melanoma in a phase II clinical trial. The response of individual l...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791835/ https://www.ncbi.nlm.nih.gov/pubmed/26981242 http://dx.doi.org/10.1186/s40425-016-0116-2 |