Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase

Eukaryal taxa differ with respect to the structure and mechanism of the RNA triphosphatase (RTPase) component of the mRNA capping apparatus. Protozoa, fungi, and certain DNA viruses have a metal-dependent RTPase that belongs to the triphosphate tunnel metalloenzyme (TTM) superfamily. Because the str...

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Detalles Bibliográficos
Autores principales: Smith, Paul, Ho, C. Kiong, Takagi, Yuko, Djaballah, Hakim, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791841/
https://www.ncbi.nlm.nih.gov/pubmed/26908574
http://dx.doi.org/10.1128/mBio.00058-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791841/
https://www.ncbi.nlm.nih.gov/pubmed/26908574
http://dx.doi.org/10.1128/mBio.00058-16

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