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Knockdown of PSCA induces EMT and decreases metastatic potentials of the human prostate cancer DU145 cells

BACKGROUND: Prostate stem cell antigen (PSCA) expression has been shown to correlate with prostatic carcinogenesis and prostate cancer (PCa) progression. The underlying mechanisms for these processes are currently unknown. Epithelial to mesenchymal transition (EMT) has been associated with the invas...

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Detalles Bibliográficos
Autores principales: Kang, Ran, Zhao, Shankun, Liu, Luhao, Li, Futian, Li, Ermao, Luo, Lianmin, Xu, Lihua, Wan, ShawPong, Zhao, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791869/
https://www.ncbi.nlm.nih.gov/pubmed/26981049
http://dx.doi.org/10.1186/s12935-016-0295-4