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Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells

BACKGROUND: Type 2 helper T-cell cytokines including IL-13 play a central role in the pathogenesis of bronchial asthma (BA). During the course of our research, our attention was drawn to dipeptidyl peptidase-4 (DPP4) as one of the molecules that were induced from bronchial epithelial cells (BECs) by...

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Detalles Bibliográficos
Autores principales: Shiobara, Taichi, Chibana, Kazuyuki, Watanabe, Taiji, Arai, Ryo, Horigane, Yukiko, Nakamura, Yusuke, Hayashi, Yumeko, Shimizu, Yasuo, Takemasa, Akihiro, Ishii, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791890/
https://www.ncbi.nlm.nih.gov/pubmed/26975422
http://dx.doi.org/10.1186/s12931-016-0342-7