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Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells
BACKGROUND: Type 2 helper T-cell cytokines including IL-13 play a central role in the pathogenesis of bronchial asthma (BA). During the course of our research, our attention was drawn to dipeptidyl peptidase-4 (DPP4) as one of the molecules that were induced from bronchial epithelial cells (BECs) by...
Autores principales: | Shiobara, Taichi, Chibana, Kazuyuki, Watanabe, Taiji, Arai, Ryo, Horigane, Yukiko, Nakamura, Yusuke, Hayashi, Yumeko, Shimizu, Yasuo, Takemasa, Akihiro, Ishii, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791890/ https://www.ncbi.nlm.nih.gov/pubmed/26975422 http://dx.doi.org/10.1186/s12931-016-0342-7 |
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