Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness

Breast tumor progression is accompanied by changes in the surrounding extracellular matrix (ECM) that increase stiffness of the microenvironment. Mammary epithelial cells engage regulatory pathways that permit dynamic responses to mechanical cues from the ECM. Here, we identify a SLIT2/ROBO1 signali...

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Detalles Bibliográficos
Autores principales: Le, Lily Thao-Nhi, Cazares, Oscar, Mouw, Janna K., Chatterjee, Sharmila, Macias, Hector, Moran, Angel, Ramos, Jillian, Keely, Patricia J., Weaver, Valerie M., Hinck, Lindsay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792073/
https://www.ncbi.nlm.nih.gov/pubmed/26975850
http://dx.doi.org/10.1083/jcb.201507054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792073/
https://www.ncbi.nlm.nih.gov/pubmed/26975850
http://dx.doi.org/10.1083/jcb.201507054

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